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Old 08-20-2009, 06:41 AM
healthyhomebiz's Avatar
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Default Autism, Transfer Factor and The DAN Protocol Part 4

Secretin This substance is helping a lot of Autistic kids, but not as many as originally thought. It is available in I.V., oral and skin patch forms. Again there is controversy as to whether the latter two forms work.

I.V. Glutathione: There have been some benefits with this therapy as far as calmness and getting rid of "tics" are concerned, as well as some acceleration in cognitive abilities. Of course, Glutathione is also available in oral and topical forms.

Metallothionein Promotion Therapy: This seems like a really exciting therapy with promising results as mentioned earlier in this synopsis. There is basically 2 phases to this protocol. The first phase is to increase the zinc and to decrease the copper. The second phase is to give the body the amino acids necessary to build the MT Protein. The MT Protein will then help the body heal and catch up in the necessary areas. Taurine interferes with Zinc absorption, so no Taurine on the days of Zinc Therapy.

A very exciting area is being researched at Harvard Mass. General Hospital where hundreds of Autistic kids are being endoscoped by Dr. Tim Buie. The findings are, that even in the absence of G.I. symptoms, there is inflammation of the gut. When the gut is given the appropriate therapies to heal, the Autistic symptoms greatly recede.

Please remember that, if you introduce your child to a new supplement, it is not unusual for the child to experience some adverse effects for a short while. These effects may include hyperactivity, skin rashes and behavioral regressions. When this happens, it does not necessarily mean that you should discontinue the supplement, unless the adverse effects are dangerous, or persistent. Usually these side effects wear off in a few days. Please remember to start with low dose and work up. If there are adverse effects, stay at this dose until the adverse effects are gone, then proceed to a slightly higher dose, etc. Your child might become hyperactive for a few days, when first starting most of these supplements. In addition, you may not see the beneficial effects of these supplements for a period of time. Also remember that just because a therapy did not work before, it does not mean that you should not re-visit that therapy at a later time, for instance, after you clean up the gut problem. Please consult your doctor about any adverse effects that persist or cause concern.


Hair analysis: The absence of mercury, in this test, does not indicate that your child's mercury level is normal. If you cannot detoxify Mercury, it will not show up excreted in your hair. Watch for elevated antimony, which can also be a problem for Autistics. Lead often shows up high in this test.

Elemental analysis: This test would show mineral deficiencies, as well as high levels of metals.

24-hour urine elemental analysis: If this test is negative, it does not mean that the mercury is not high. In many cases, one would have to use a chelating agent to do a challenge test. In the challenge test, the chelating agent moves the mercury from the intracellular space into the extracellular space, so that it can be measured. If your child is not toilet-trained, you might want to do a 6-hour or 12-hour urine test, instead.

Plasma amino acids: These kids cannot digest well because of poor pancreatic and/or liver, biliary function. Often amino acid supplementation helps mental function. Many key enzymes cannot be produced in amino acid deficiencies. The 24-hour urinary amino acid works better than the plasma amino acid if your child is toilet-trained.

C.D.S.A. (Comprehensive digestive stool analysis): A lot of autistic children show very poor ability to absorb fat, hence, can be very deficient in vitamins A, D, E and beta-carotene. This test indicates what is happening to digestion and absorption. It would tell you how to repair the bowel condition and what is needed to help digestion.

Anti-Candida Antibody Test - IgA, IgG, IgM: You need to monitor the yeast level every two or three years after treatment, as recurrence often happens, especially when you are chelating.

Food allergy test - IgE, IgG: In food allergies, the IgE mediated response is obvious - you get an immediate reaction like hives, itchy eyes or difficulty with breathing. With the IgG mediated response, it's a delayed reaction, so that you may not even get the stuffy nose or headache until three days later. Please note that food allergens change, so that it is a good idea to repeat this test every year or two. The food allergens act as toxins and would interfere with your child's mental functioning, etc. For instance, one child became toilet-trained, two weeks after the allergens were removed. (ImmunoLab does a good job on this test).

CBC and Differential, CHEM 25: This is just to make sure that the blood count is normal and that the liver and kidneys are working well enough to chelate, if necessary.

Serum ceruloplasmin and copper that need to be tested in acid etched test-tubes and plasma Zinc done in EDTA test-tubes- this is done before and after Zinc loading before the actual Metallothionein Promotion takes place.

All these tests are available through Great Smokies Lab, 1-800-522-4762, (except the anti-Candida antibody - that is from ImmunoSciences Lab). Test # 8 can be done in any lab at all. Your doctor can also consult a Great Smokies staff doctor to go over all the results and recommendations, once the results are back. Dr. Pangborn is one of the world's geniuses in Biochemistry; he consults for Great Smokies.

The other labs that are also excellent for these tests are:

Biocentre Lab






Meridian Valley Lab




Dr.'s Data Lab


Please note that only your doctor can order test kits from these labs.


Dr. Sidney Baker's Book, "Detoxification and Healing" ISBN 0-87983-709-8 Publisher: Keats Publishing Inc. This book is easy to read and is very important to understanding Autism, or how to stay healthy yourself.

Defeat Autism Now! Protocol: $25.00 Explanation of all of this material, more accurately and more scientifically. Phone: 619-281-7165 (Autism Research Institute). About Us

"Children with Starving Brains", by Jacquelyn McCandless M.D. A book that every Autistic child's parent should read and study ISBN 1-883647-09-6. It is a well-written book on the Defeat Autism Now! protocol.


Make sure your child is balanced nutritionally - i.e. amino acids, vitamins, minerals etc., before chelation. If the child is very out of balance, chelation may lead to seizures (especially if the child is low in magnesium or taurine)

Do not take mineral supplements on the days of chelation, but make sure you do take them on "off" days. Even though the agents are not supposed to affect calcium and magnesium, I found that taking extra amounts of these reduces the muscle twitching and headaches. The revision in the chelation protocol advises us to take some Zinc and some selenium even on the days of chelation. We find that doing this helps cut down the irritability by quite a bit.

In dosing of the DMSA or DMPS, chelating agents, remember to remind your doctor, to "go low" and to "go slow"!

Make sure you have a knowledgeable doctor supervising the chelation - what blood parameters to monitor etc. Dr. Rimland's institute, Autism Research Institute, has a list of doctors who are familiar with the Defeat Autism Now! protocol.

There are three agents for chelation of mercury:

DMPS (Heyl is the purest brand) oral, I.V. or I.M.

DMSA (Chemet, Succimer). (Kirkman makes a very palatable form) oral.

DMSA with ALA (alpha lipoic acid) oral.

Allithiamine- this is a mild chelator and is used as a cream on the soles of the feet. The advantage of this treatment is that you don't end up with so many problems with over-growth of yeast and different bacteria as you do with DMSA or DMPS.

There are many chelation protocols, please consult either the web site of the Autism Research Institute About Us. Most chelation is done orally; some doctors implement the oral chelation with I.M. shots of DMPS.

Please note that most of the information from this Defeat Autism Now! Conference (including the Autistic child's underlying inability to detoxify, deficiency states and toxicity and the treatments as discussed), is not yet widely accepted by the medical profession. The conventional medical community takes a very long time to embrace and accept new ideas. Don't be surprised if your doctor regards this information with skepticism. You may need to find a Defeat Autism Now! Doctor (see # 4 above) or a doctor who is open-minded enough to supervise the testing and treatment with you.
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