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  #1 (permalink)  
Old 10-05-2010, 10:32 AM
HealthyMomma's Avatar
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Default Migraines "B" Gone.....


Many of you probably already knew that B vitamins help

reduce the frequency and severity of migraines. That information has been

around for years.

What these investigators did was combine that

information with the much newer science of

nutrigenomics and showed that some migraine sufferers

benefited much more from B vitamin supplementation

than others.

There is a genetic polymorphism called MTHFRC677T

(Don't you love scientific nomenclature). All you

really need to know is that people with this genetic polymorphism have

significantly higher requirements for folic acid and slightly higher

requirements for vitamins B6 and B12.

People with this polymorphism also tend to have

elevated levels of homocysteine and increased risk of

diseases that are influenced by folic acid, B6 & B12.

More to the point, this polymorphism significantly

increases the risk of migraines. For example, the

frequency of the MTHFRC677T polymorphism in the general population is only

5-10%, but it approaches 40% in migraine sufferers.

This was a double blind, placebo controlled study

designed to determine the effectiveness of B vitamins

(2 mg folic acid, 25 mg B6 and 400 ug B12) in

decreasing the frequency and severity of migraine

attacks in long term migraine sufferers.

The migraine sufferers were divided into two groups, a

B vitamin group and a placebo group, and were evaluated

at 3 and 6 months.

Migraine disability in the B vitamin supplement group

decreased from 60% to 30% (a highly significant

decrease) during that 6 month period, while there was

no decrease in the placebo group.

When the groups were stratified according to the

MTHFRC677T polymorphism the reduction in migraine

disability was an even more impressive 76% to 28%. No significant decrease

in migraine disability was observed in either the placebo group or the B

vitamin group without the MTHFRC677T polymorphism.

In short, some people experienced dramatic relief from

their migraines by supplementing with B vitamins while

others experienced little or no relief - and the

difference in response was determined by their genetic


So what about you?

If you are a migraine sufferer, B vitamin

supplementation is worth a try. You should know within

3 to 6 months whether you are one of the fortunate ones

who will experience dramatic relief from something as

simple and risk-free as B vitamin supplementation.

If you don't want to wait 6 months, just try a holistic approach. Omega-3

fatty acids (fish oil), calcium and magnesium help many migraine sufferers -

and their effects are independent of the MTHFRC677T polymorphism.

A holistic approach that includes B vitamins, omega-3

fatty acids, calcium & magnesium is likely to offer

some benefit to just about anyone who suffers


To Your Health!

Dr. Stephen G Chaney
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  #2 (permalink)  
Old 10-06-2010, 12:52 PM
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Location: Tennessee
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Such great information! Thanks for posting this.

I have been using this type of vitamin therapy for some time, and I did have some relief. I take B6, B12, omega 3, calcium, and magnesium. Definitely saw some improvements, but over time, my migraines did start to creep back. While they weren't as intense or as long-lasting, they did come back. I think for the most part it is hormonal....

I would like to add, though, that I have been migraine free for the past 3 months when I added weekly chiropractor visits to my vitamin regimen. I had heard that might give me some relief, and thought if it meant not taking any medications, why not? I've also heard, although have not tried personally, that some migraine sufferers also get relief through acupuncture (sp?).

So far so good! Just thought I would share my experience.


Last edited by mandm'smommy; 10-06-2010 at 12:56 PM.
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Old 10-06-2010, 01:11 PM
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Thanks, Melissa, for coming and sharing with all of us what your "experience" has been in regards to migraines! I can't even imagine how tough it must be for those that deal with migraines all the time and who aren't getting the relief that they would so appreciate!

Glad you found the information helpful and thanks again for taking the time to come and share with all of us that you'd agree that this type of vitamin regimen is really a great start to better health!

Take care............
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Old 10-06-2010, 02:03 PM
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Hey, Amber,

I am all about finding an alternative to OTC and other medications (if possible--I don't shun medicine altogether, but when there is another alternative that works, I get excited) and when science and research backs up something, then I say, "Awesome! It's at least worth a try!!"
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Old 10-23-2010, 02:41 PM
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This is great info! Calcium Magnesium seems to help mine, but like you Melissa, they seem to creep back here & there. Mine are hormonal. They magically disappeared while I was pregnant...I also made sure I took my B vitamins and cal/mag everyday, so I'm sure that helped. I also do very well with chiropractic. Massage is also very good for reducing muscle tension that can make migraines worse. It can seem hopeless sometimes when dealing with migraines, so I'm sure this is encouraging to many!
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b-complex, migraines, shaklee

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