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View Full Version : Mangosteen Facts....

08-14-2006, 09:53 AM
For centuries the traditional medical healers of India, China, Malaysia, Thailand the Philippines and Vietnam have employed Mangosteen for its health benefits.

In the last 150 years the plant has been transported to Africa, the Caribbean, Australia and South America where both researchers and medical practitioners alike have studied and utilised its healing and protective properties.

In India, Thailand and China, preparations from the rind are used as antimicrobial and antiparasitic treatments for dysentery and other forms of infectious diarrhoea.

The plant's astringent qualities are useful in preventing dehydration and the loss of essential nutrients from the GI tract of diarrhoea sufferers.

The Chinese and Thais also take advantage of the mangosteen's antimicrobial and antiseptic properties to treat infected wounds, tuberculosis, malaria, urinary tract infections, syphilis and gonorrhoea.

It has long been recognised in Asia that the Mangosteen has apperently powerful anti-inflammatory powers and is reported to be effective in treating eczematous and other hyperkeratotic skin conditions.

In the Caribbean, known as " eau de Creole ", a tea made from Mangosteen is used as a tonic for fatigue and malaise, universal symptoms experienced by millions around the world..

Brazilians use a similar tea as a de-worming agent and digestive aid. In Venezuela, parasitic skin infections are treated with poultices of the fruit while Filipinos employ a fruit extract to control fever.

Unlike most medicinal plants, the phytoceuticals of the mangosteen have been widely studied by medical and pharmacological researchers.

Research has unearthed over forty scientific papers in which biochemically active components of the mangosteen have been rigorously examined in the laboratory. While we continue to search out and examine dozens of other papers, it is already evident that the multiple health benefits of the fruit are supported by scientific investigation.

See pubmed.com

Here is just a glimpse of what has been found.

Among the phytoceuticals in the mangosteen is a newly discovered class of highly active substances called 'Xanthones'? Garcinia Mangostana's Xanthones are still being investigated, and to date, 43 xanthones have been identified and several of them intensely studied.

The whole fruit of the mangosteen has been found to :

support microbiological balance
maintain immune system health
promote joint flexibility
provide positive mental support

References and Studies:

Tapiero, H., et. al. “Polyphenols: do they play a role in the prevention of human pathologies?” Biomedicine & Pharmacotheraphy; 2002, 56 (4):200-207

Huang, D., et. al. “High-throughout assay of oxygen radical absorbency capacity using multichannel liquid handling system coupled with a microplate florescence reader in 96 we format.” Journal of Agricultural and Food Chemistry: 2002 50 (16): 4437-4444

Mangosteen in the Columbia Encyclopedia, 6 th edition, Columbia University Press 2003

Parkinson. R. “Mangoes, Lychees and Mangosteen.: Chinese Cuisine 2004

Nakatani, K. , et. al. “gamma-Mangostin inhibits IkappaB Kinase Activity with and decreases Lipopolysaccaride-induced cyclooxgenanase-2 Gene Expression in C6 Rat glioma Cells.” Molecular Pharmacology; June 24, 2004

Jiang, D.J. e. al. “ Pharmacological effects of xanthones as cardiovascular protective agents.” Cardiovascular Drug Reviews , 2004, 22(2):91-102

Biochem Pharmacol, 2002 Jan 1;63(1):73-9

Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives – J. Nat Prod 1997 May; 60 (5):519-24

Active constituents against HIV-1 protease from Mangosteen- Planta Med 1996 Aug;62(4):381-2

Mangostin inhibits the oxidative modification of human low density lipoprotein- Free radic Res. 1995 Aug.:23(2):175-84

Antiproliferation, antioxidation and induction of apoptosis by Garcinia mangostana on SKBR3 human breast cancer cell line J.Ethnopharmacol, 2004 Jan:90(1):161-6

Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines

J.Nat Prod. 2003 Aug;55(8):1124-7

09-13-2006, 01:37 PM
Hi DJ,

I love this post and share.

It was nice talking to you and Craig yesterday.

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